BDBM35727 sulfonamide deriv., 5b

SMILES NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)c(F)c1

InChI Key InChIKey=XAKMDYVUOKFDSL-UHFFFAOYSA-N

Data  12 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 35727   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35727(sulfonamide deriv., 5b)
Affinity DataKi:  390nM ΔG°:  -8.74kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35727(sulfonamide deriv., 5b)
Affinity DataKi:  390nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35727(sulfonamide deriv., 5b)
Affinity DataKi:  390nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair